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| Avigan Begins Testing on Corona Patients - Heallink |
Avigan is approved for use as a treatment for flu and Ebola outbreaks. However, for now the drug has been tested as a potential treatment for corona virus.
Avigan is the brand name of the drug favipiravir. The drug was developed by what is now known as Fujifilm Toyama Chemical and was approved for use in Japan in 2014.
But in Japan, it is only approved for use in flu outbreaks that are not effectively treated by existing medicines. This is not available on the market and can only be produced and distributed at the request of the Japanese government.
Favipiravir works by blocking the ability of the virus to replicate in cells.
However there are some safety issues: it has been shown in animal studies to influence fetal development, which means it is not given to pregnant women, and some doctors say they will not recommend it for children or adolescents.
Quoting AFP, some doctors started trying favipiravir to treat Covid-19 patients early on, arguing that their anti-viral properties could be applied.
Some preliminary results suggest the drug can help shorten recovery time for patients, with the Chinese ministry of science and technology calling it "an excellent clinical outcome".
There are currently around five clinical trials in progress in countries including the US, Italy and Japan, where Fujifilm announced it will test the efficacy of the drug in a group of 100 patients until the end of June.
Studies in Japan will involve administering drugs for up to 14 days for patients between 20 and 74 with mild pneumonia.
Gaetan Burgio, a geneticist at the Australian National University College of Health and Medicine, said the trial would look at various factors.
They include clinical outcomes - meaningful effects on fever, coughing, oxygenation, recovery time and time spent in the hospital - as well as how quickly the virus cleans the system, along with x-rays or CT scans for pneumonia.
"If we see a significant decrease in clinical outcomes and lower viral load in the favipiravir group, this will be a good sign for larger scale clinical trials," he told AFP.
Favipiravir works by blocking the ability of the virus to replicate in cells.
However there are some safety issues: it has been shown in animal studies to influence fetal development, which means it is not given to pregnant women, and some doctors say they will not recommend it for children or adolescents.
Quoting AFP, some doctors started trying favipiravir to treat Covid-19 patients early on, arguing that their anti-viral properties could be applied.
Some preliminary results suggest the drug can help shorten recovery time for patients, with the Chinese ministry of science and technology calling it "an excellent clinical outcome".
There are currently around five clinical trials in progress in countries including the US, Italy and Japan, where Fujifilm announced it will test the efficacy of the drug in a group of 100 patients until the end of June.
Studies in Japan will involve administering drugs for up to 14 days for patients between 20 and 74 with mild pneumonia.
Gaetan Burgio, a geneticist at the Australian National University College of Health and Medicine, said the trial would look at various factors.
They include clinical outcomes - meaningful effects on fever, coughing, oxygenation, recovery time and time spent in the hospital - as well as how quickly the virus cleans the system, along with x-rays or CT scans for pneumonia.
"If we see a significant decrease in clinical outcomes and lower viral load in the favipiravir group, this will be a good sign for larger scale clinical trials," he told AFP.
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